Simplifying HPLC-Based Protein Analysis
Monitoring titer, aggregates, and charge variants is essential during the discovery and development of therapeutic antibodies.
The Proteometer® gives biopharma R&D a simpler, shorter path than standard size-exclusion chromatography by eliminating the pre-analysis Protein A capture step.
How We Help
Typical analytical testing of proteins with an Fc region requires multiple personnel, consumables, and expensive instruments.
The Proteometer workflow integrates sample preparation, selective fluorescent labeling, and size-based separation in a single reactor, eliminating the need for conventional Protein A capture before analysis. This provides titer, aggregate content, and charge variant results with fewer handling steps, lower consumable use, and less workflow complexity.
Accessing critical quality attributes earlier helps scientists streamline clone selection, process optimization, biosimilar comparability, and development-stage monitoring.
Testomonials
"We use the Proteometer-L Kit for the rapid analysis of mAbs and bispecifics for titer and aggregate content from cell-free filtrate samples.
It eliminates sample preparation steps, Protein A purification, and mass spectrometry analysis steps.
I would recommend the Proteometer to any pharmaceutical company to quickly and accurately quantitate titer and aggregate content."
Harsha Gunawardena
Johnson & Johnson
Senior Principal Scientist
“Sample preparation has long been a bottleneck in pharmaceutical research. Every time you touch a sample, you risk compromising it.
The beauty of Novilytic's Proteometer is that it removes this step entirely. It's a groundbreaking innovation developed by Dr. Regnier and his brilliant team, yet it is intuitive enough for anyone to use.
The Proteometer is a game-changer, and we are thrilled to bring it to our global customer base."