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Simplifying HPLC-Based Protein Analysis

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Monitoring aggregates, titer, and charge variants is essential in therapeutic antibody discovery and development. 

The Proteometer gives biopharma R&D a simpler path to critical protein-quality data by eliminating the need for pre-analysis Protein A capture.

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Streamlining Your Workflow 

Typical analytical testing of proteins with an Fc region requires multiple personnel, consumables, and expensive instruments. 
 

The Proteometer workflow integrates selective fluorescent labeling and size-based separation in a single HPLC workflow, eliminating conventional pre-analysis sample preparation and Protein A capture.

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The result is aggregate, titer, and charge variant data with fewer handling steps, lower consumable use, and less workflow complexity – helping scientists streamline clone selection, process optimization, biosimilar comparability, and development-stage monitoring.

Testimonials

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"We use the Proteometer-L Kit for the rapid analysis of mAbs and bispecifics for titer and aggregate content from cell-free filtrate samples.

 

It eliminates sample preparation steps, Protein A purification, and mass spectrometry analysis steps.

 

I would recommend the Proteometer to any pharmaceutical company to quickly and accurately quantitate titer and aggregate content."

Harsha Gunawardena
Johnson & Johnson
Senior Principal Scientist

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“Sample preparation has long been a bottleneck in pharmaceutical research. Every time you touch a sample, you risk compromising it. 

 

The beauty of Novilytic's Proteometer is that it removes this step entirely. It's a groundbreaking innovation developed by Dr. Regnier and his brilliant team, yet it is intuitive enough for anyone to use.

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The Proteometer is a game-changer, and we are thrilled to bring it to our global customer base."

Robert Fitzgerald
Avantor, Inc.
Manager, Chromatography Portfolio

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