Proteometer-L Kit
​The Proteometer-L Kit transforms any LC into an analytical system capable of identifying and quantifying titer and relative aggregate content in crude culture filtrate in <10 minutes, without sample preparation.
It works with mAbs, multi-specifics, and recombinant proteins containing an Fc domain and eliminates sample preparation and method development.
Features & Benefits:
​​​
-
mAb titer + aggregate measurement: One assay for two critical attributes
-
No Protein A purification required: Reduces costs
-
No sample pretreatment: Reduces hours of sample prep
-
Direct analysis from CFB: HCP removal is not needed
-
No method development: Reduces time until method development
-
Plug-and-play kit for any LC: Easy adoption - no software needed
-
Low sample volume (≤ 10μL): Reduced impact on processing
Kit Components:
​​
-
Proteometer-L Reactor
-
Proteometer-L Reagent
-
Proteometer-L Buffer
-
Proteometer-L Reconstitution Reagent
-
Instructions for Use​​
At-line Applications:
-
Drug Discovery
-
Clone Selection
-
High Throughput Screening
-
Product Characterization
-
PR&D and Manufacturing
​​​
Additional Product Information
​​​​​​
​
​
​
​​​​​
TESTIMONIALS
"We use the Proteometer-L Kit for the rapid analysis of mAbs and bispecifics for titer and aggregate content from cell-free filtrate samples.
It eliminates sample preparation steps, Protein A purification, and mass spectrometry analysis steps.
I would recommend the Proteometer to any pharmaceutical company to quickly and accurately quantitate mAb titer and aggregate content."
Harsha Gunawardena
Senior Principal Scientist
Johnson & Johnson
​
“Novilytic’s Proteometer is a disruptive breakthrough that finally solves the FDA's requirement to continuously monitor t-mAb proteoforms during fermentation.
The approach improves product safety, reduces COPQ and post release testing, and paves the way for real-time product release, reducing inventory costs.
The solution combines novel sample handing and artificial intelligence with proven analytical technology that is easy to deploy and support, and provides near instantaneous ROI.”
Martin Long, BSc.
Performance Validation, Inc. – President & CEO
(Analytical Sciences Business, Brooks Life Sciences, Thermo, Perkin Elmer)
"Sample preparation has long been a bottleneck in pharmaceutical research. Every time you touch a sample, you risk compromising it.
The beauty of Novilytic's Proteometer is that it removes this step entirely. It's a groundbreaking innovation developed by Dr. Regnier and his brilliant team, yet it is intuitive enough for anyone to use.
​
The Proteometer is a game-changer, and we are thrilled to bring it to our global customer base."