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Proteometer-L Kit 

Proteometer-L Kit 

The Proteometer-L Kit transforms any LC into an analytical system capable of identifying and quantifying titer and relative aggregate content in crude culture filtrate in <10 minutes, without sample preparation.


This plug-and-play solution provides savings of over $100,000 per day by eliminating the hours of sample preparation traditionally required for molecular analysis.

Additional Product Information


At-line Applications:

  • Drug Discovery

  • Clone Selection

  • High Throughput Screening

  • Product Characterization

  • PR&D and Manufacturing

Features & Benefits 

  • Direct analysis from clarified fermentation broth

  • mAb Titer and aggregate detection and quantification in one assay

  • No mass spec needed!

  • Allows for multiplexing, unlike traditional ELISA analysis

  • Eliminate sample pretreatment

  • Utilize your existing instruments

  • ≤ 10μL sample of clarified fermentation broth

  • < 10 mins per analysis

Kit Components

  • Proteometer-L Reactor

  • Proteometer-L Reagent

  • Proteometer-L Buffer

  • Proteometer-L Reconstitution Reagent

  • Instructions for Use

L Open.jpg


Architectural Structure

"We use the Proteometer-L Kit for the rapid analysis of mAbs for titer and aggregate content from cell-free filtrate samples. It eliminates sample preparation steps,  Protein A purification, and mass spectrometry analysis steps.


I would recommend the Proteometer to any pharmaceutical company to quickly and accurately quantitate mAb titer and aggregate content."

Harsha Gunawardena
Principal Scientist, Janssen Pharmaceuticals (Johnson & Johnson's research division) 

Architectural Structure

“Novilytic’s Proteometer is a disruptive breakthrough that finally solves the FDA's requirement to continuously monitor t-mAb proteoforms during fermentation.


The approach improves product safety, reduces COPQ and post release testing, and paves the way for real-time product release, reducing inventory costs. 


The solution combines novel sample handing and artificial intelligence with proven analytical technology that is easy to deploy and support, and provides near instantaneous ROI.”

Martin Long, BSc.
Performance Validation, Inc. – President & CEO
(Analytical Sciences Business, Brooks Life Sciences, Thermo, Perkin Elmer)

Architectural Structure

"As analytical tools have matured for the quality control and characterization of isolated biopharmaceuticals, the application of advanced analytical systems to dynamically contribute to process monitoring and control in complex bioreactors is critical for enhanced process efficiency and product quality.


The Proteometer is expected to play a central role in the development and commercialization of next-level biological manufacturing control strategies. The integration of complementary bioprocess analytical data facilitates decision-making through a powerful link between the manufacturing space and the QC laboratory."

Eugene L. Inman, Ph.D.
Pharmaceutical Quality Consultant
Retired Eli Lilly and Company

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